Metformin hydrochloride is an orally administered biguanide widely used in clinical medicine.

盐酸胍是目前广泛用于床医学的胍类降。

All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro.All of the other compounds tested were either additive or antagonistic.

【献摘要】The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed.