When this happens, TRH also stimulates prolactin release - so hyperprolactinemia and amenorrhea occur.

与此同时，TRH也刺激泌乳素的分泌，所以也会出现高泌乳素血症和闭。

There are also diseases that can cause osteoporosis like Turner syndrome, hyperprolactinemia, Klinefelter syndrome, Cushing syndrome, and diabetes mellitus.

也有一些疾病会导致质疏松，如Turner综合征、高催乳素血症、先天性育不全综合征、皮质醇增多症以及糖尿病。

One cause is hyperprolactinemia, or excessive prolactin secretion by pituitary lactotroph cells, which is frequently seen with a benign pituitary tumor called a prolactinoma.

一个原因是高泌乳素血症，即垂体泌乳素细胞分泌过多泌乳素，大多并良性的垂体肿瘤，称为泌乳素瘤。

Causes of secondary amenorrhea can also cause primary amenorrhea, and they include functional hypothalamic amenorrhea, polycystic ovary syndrome, hyperprolactinemia, premature ovarian failure and Asherman syndrome.

继性闭的病因也可以导致原性闭，包括功能性下丘脑性闭、多囊卵巢综合症、高泌乳素血症、卵巢早衰以及Asherman综合征。