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Osmosis-呼吸

For children, inhalers should be used with spacers.

对于儿童,吸入器应该与一起使用。

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Osmosis-遗传

And in between these repeats are unique sequences called spacers.

这些重复间的独特序列被称" 间隔序列" 。

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Osmosis-呼吸

The spacer helps get the medication deep into the lungs instead of just in the mouth.

可以帮助药物深入肺部,而不仅仅停留在口腔内。

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影视剧中的医学知识

This is what a spacer looks like.

这就是垫片的样子。

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Life Noggin

Well, between each repeating section of DNA, there are short sequences of DNA called spacers.

那么,在 DNA 的每个重复部分间,都有称间隔区的短 DNA 序列。

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Life Noggin

Once the virus has been identified, the DNA in the spacer is copied into an RNA molecule.

一旦病毒被识别,间隔子中的 DNA 就会被复制到 RNA 分子中。

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Life Noggin

But if the virus is new, DNA from it must first be inserted into the CRISPR sequence as a new spacer.

但如果病毒是新病毒,它的 DNA 必须首新的间隔区插入 CRISPR 序列。

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Osmosis-遗传

Now it turns out that the spacers in CRISPR locations are kind of a historical record of DNA viruses that have previously infected the host.

现在证明CRISPR位点上的间隔序列是早感染过宿主的DNA病毒留下的一种历史记录。

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Osmosis-遗传

So when a DNA virus gets into a host cell, certain fragments of it called Protospacers are incorporated into the host's genome, becoming the spacers in CRISPR locations.

当DNA病毒进入宿主细胞时,其被称" 原间隔序列" 的特定片段会被整合进入宿主基因组变成CRISPR位点上的间隔序列。

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Osmosis-呼吸

The inhaler, spacer, and mask can be bulky to carry around, but all people with asthma need to have their rescue medicines close by at all times.

吸入器、和面罩携带起来可能比较笨重,但是所有哮喘患者需要随时都携带他们的救援药物。

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Osmosis-遗传

What's left are mature crRNAs each made of the complements to both the 3 prime repeat and about 20 nucleotides of a spacer, still bound to tracrRNA.

留下的成熟crRNA依然与tracrRNA结合,每一个都由重复序列互补链的3'端和间隔序列互补链约20个核苷酸组成。

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Life Noggin

So, when a virus invades a cell, if there is an associated spacer already there, meaning it's on the most-wanted list, the bacterium can go on to destroy the virus.

因此,当病毒入侵细胞时, 如果那里已经有一个相关的间隔子,这意味着它在最想要的名单上, 那么细菌就可以继续摧毁病毒。

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