Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法霉素为起始原料,经水解、乙酰化、碳酸酯化、氧化、脱碳酸酯化、酰化、甲酸酯化和合等反应合成目标化合物。