One example is cholecystokinin, which is produced in response to food by cells in the upper small bowel.

一个例子是收缩素，它是小肠上段细胞对食物产生反应而产生。

Less energy expenditure makes you more lethargic, less cholecystokinin means more hunger, less leptin signalling means more hunger and more ghrelin also means you're hungrier.

更少消耗会让人更嗜睡，更少收缩素、更少瘦素信号以及更胃促生长素都会增加饥饿感。

The cholecystokinin makes its way to the gallbladder, the thin walled, green sac snuggling up against the liver, and signals it to squeeze out some bile through the cystic and bile ducts into the small intestine.

当收缩素到达（位于右方肋骨下肝脏后方梨形袋构造），在激素信息指引下开始收缩，将汁通过管和管排入小肠内。

As an October 2011 study in the New England Journal of Medicine says: " Caloric restriction results in acute compensatory changes, including profound reductions in energy expenditure and levels of leptin and cholecystokinin and increases in ghrelin and appetite."

正如 2011 年 10 月发表在《新英格兰医学杂志》上一项研究所说：“热限制会导致急性代偿性变化，包括消耗、瘦素和收缩素水平显著降低，以及胃饥饿素和食欲增加。”