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The epigenome is a molecular marking system that controls gene expression without altering the DNA sequence.

Image credit: Dreamstime表观基因是在不改变DNA制基因表达分子标记系统。

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VOA Special 2015年3月合集

Mr. Sabanayagam studies the epigenome as it relates to microgravity.

Sabanayagam研究了的表组基因组。

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连线杂志

And that epigenome is constantly changing.

表观基因组是不断变化的。

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VOA Special 2015年3月合集

After about a week the scientists take out the worms. They look for changes in the worms' epigenome.

周后科学家将蠕虫取出,然后观察蠕虫表观基因组的改变。

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连线杂志

The epigenome is kinda like Play-Doh on the genome.

表观基因组有点像基因组上的橡皮泥。

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TED-Ed(视频版)

The epigenome also mediates a lifelong dialogue between genes and the environment.

表观基因组同样导终生对话在基因和环境中。

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TED-Ed(视频版)

As twins get older, their epigenomes diverge, affecting the way they age and their susceptibility to disease.

当双胞胎慢慢长大,它们的表观基因组不样了,影响了他们的寿命和他们受疾病的损害程度。

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VOA Special 2015年3月合集

The epigenome can be changed by the environment. And those changes pass from one generation of worms to the next.

表观基因组可以被环境改变,这些改变从代蠕虫传递代。

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连线杂志

But in addition to the primary sequence of DNA, in addition to the As, Ts, Cs, and Gs, there's our epigenome.

但是除了 DNA 的初始序列,除了 A,T,C 和 G,还有我们的表观基因组。

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TED-Ed(视频版)

The set of all of the chemical tags that are attached to the genome of a given cell is called the epigenome.

所有的化学标记都依附于染色体组,属于个特定的细胞被称作是表观基因组。

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TED-Ed(视频版)

A balanced lifestyle that includes a healthy diet, exercise, and avoiding exposure to contaminants may in the long run create a healthy epigenome.

个平衡的生活方式包括健康的饮食,锻炼,和避免暴露于污染从长远来看,能够创造个健康的表观基因组。

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TED-Ed(视频版)

Your mother's or your father's experiences as a child, or choices as adults, could actually shape your own epigenome.

你的母亲或者父亲作为孩子的经历,或者成为成年人后的选择,事实上可能形成了你自己的表观基因组。

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TED-Ed(视频版)

Each of the approximately 200 cell types in your body has essentially the same genome but its own distinct epigenome.

大约有200细胞类型在你的身体里,每个细胞类型都有相同的染色体组但是拥有他们自己不同的表观基因组。

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自然杂志:人体健康

So when we're young, our epigenome is pristine, it's set with genes on and genes that  are off that maintain a cell's identity.

所以当我们年轻的时候,我们的表观基因组是原始的,它由维持细胞特性的基因和关闭基因组成。

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