1.Method Treatment of 8,9 anhydroerythromycin 6,9 hemiketal with iodine in the alkaline solution provided corresponding N monodemethylated 12 membered ring erythromycin derivative.
2.What they did was they took E.coli, which can be a pretty nasty pathogen, and they treated it with two common antibiotics: doxycycline and erythromycin.