This enzyme normally breaks down a lipid called GM2 ganglioside.

HEX-A正常情况能降叫做GM2神经节苷的质。

All right, as a quick recap, Tay-Sachs disease is a lysosomal storage disease that results in a buildup of GM2 ganglioside in neurons of the central nervous system.

好，快速回顾：Tay-Sachs溶酶体贮积，能引起中枢神经系统神经元中GM2神经节苷贮积。