Different hemoglobins have different combinations of these chains.

不同的白是肽链的不同组合。

And each of those hemoglobins can bind to four oxygen molecules.

而一个白能与4个氧分子结合。

A hemoglobin tetramer with two alpha-globin and two mutated beta-globin proteins is called sickle hemoglobin, or HbS.

由两条α-珠白与两条变异β-珠白构成的白四聚体，称作镰状白，或HbS。

When red blood cells do not have enough hemoglobin, oxygen doesn't get to all parts of the body.

当细胞没有足够的白时，氧气就无法到达身体的各个部位。

Now, in the blood, each red blood cell has millions of hemoglobin proteins.

液中，每个细胞都有数百万的白。

These disorders are caused by genetic mutations that prevent the normal production of hemoglobin.

这些疾病是由阻止白正常产生的基因突变引起的。

Normally, hemoglobin is made up of four globin chains, each bound to a heme group.

正常情况下，白由4条珠白链组成，每条珠白链都与一个素基团结合。

They are made in the bone marrow and contain a special ion-containing protein called hemoglobin.

它们是骨髓中形成的，含有一白的特殊含离子白质。

Hemoglobin electrophoresis can be done to see which hemoglobin types are present.

白电泳可用来鉴别白的类型。

They also have a special type of hemoglobin, the molecule in the blood that transports oxygen.

他们同时有着一特殊的白，这分子液中负责运输氧气。

Carbon monoxide and oxygen compete to bite hemoglobin in your blood, which stresses the circulatory system.

一氧化碳和氧气争先恐后地与液中的白结合，这给液循环系统带来了压力。

These four globin chains combine in different ways to give rise to different kinds of hemoglobin.

这四珠白链以不同的方式结合，形成不同类型的白。

It says that an increase in carbon dioxide results in hemoglobin proteins releasing oxygen into the tissues.

当液中的二氧化碳增多时，白会把细胞绑定的氧气释放到人体组织中去。

Sickle cell disease is caused by defective hemoglobin, which is the oxygen-carrying protein in red blood cells.

镰状细胞病是由有缺陷的白引起，后者是细胞中的携氧白。

Those ions bind to the hemoglobin, changing its shape yet again, further lowering its affinity for oxygen.

这些离子与白结合，再次改变其形状，进一步降低其对氧的亲和力。

One of the adaptations that the body makes after it's been at high altitude is to make more hemoglobin.

高海拔地区，身体的其中一个适应就是制造更多的白。

To treat sickle cell disease, researchers used CRISPR to make the body produce the fetal form of hemoglobin.

为了治疗镰状细胞病，研究人员使用 CRISPR 使身体产生胎儿形式的白。

Their hemoglobin is much stickier for oxygen than ours and can pick oxygen up even when it's scarce.

它们的白比我们的更加粘，能够氧气很稀薄的情况下也能进行收集。

But the fact is, hemoglobin's affinity for oxygen isn't always the same.

但事实是，白对氧气的亲和力并不总是一样的。

Finally, the diagnosis is confirmed by genetic testing to look for hemoglobin gene mutations.

最后，可以通过基因检测寻找异常白基因进行确诊。