Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.

甲基丙二是由于甲基丙二酰辅酶A酶或其辅酶苷钴胺素缺陷所致的一种遗传性代谢疾。

Prosthetic enzyme of mutase, catalyze reactions of group, mainly methyl, metachoresis in the interior of substrate molecule.

酶的辅酶，催化底物分子内基团(主要为甲基)的反应。