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Osmosis-泌尿

Finally, there are some rare stones made of xanthine, which, just like uric acid, is a byproduct of purine breakdown.

最后,还有由黄嘌呤形成罕见结石,同尿酸一样,是嘌呤分解

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Osmosis-泌尿

Since uric acid is a breakdown product of purines, a very common reason for high levels of uric acid is consuming lots of purines.

由于尿酸是嘌呤分解,故高尿酸是大量摄入嘌呤结果。

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Osmosis-肌骨

To understand where the uric acid comes from, let's start with purines, which, together with pyrimidines, are nature's most common nitrogen-containing heterocycles.

为了说明尿酸从何而来,让我先来了解嘌呤和嘧都是自然界中最常见含氮杂环。

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Osmosis-肌骨

Xanthine oxidase is an enzyme involved in the breakdown of purines to uric acid, so inhibiting this enzyme results in less uric acid production.

黄嘌呤氧化酶负责分解嘌呤为尿酸,所以抑制这个酶,就可以减少尿酸生成。

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Osmosis-肌骨

These crystals can form as a result of increased consumption of purines, like from consuming purine-rich foods like shellfish, anchovies, red meat or organ meat.

这种结晶成因有嘌呤摄入过多,如摄入富含嘌呤,像是贝壳、沙丁鱼、红肉或动内脏。

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Osmosis-肌骨

Also, though, they can result from increased production of purines, for example high-fructose corn syrup containing beverages could contribute to the formation of uric acid by increasing purine synthesis.

但同时,这也可能是由于嘌呤生成过多,如高果糖饮食、玉米糖浆饮料会促进嘌呤合成,从而生成尿酸。

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