Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

研究具有环丙基结构的三醇化合物的抗真菌活性。

OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

介绍咪、三、烯丙胺、抗生素身用抗真菌药的研发进展市场应用趋势。

Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

戊醇属三菌剂,可抑制真菌中麦角甾醇的生物合成,主要商品有:立克莠、富力库、菌立克三种。

By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

以2-芳基-5-巯基-1，3，4-三为原料，在稀碱存在下与二卤代烷反应合成了10个新的标题化合物。

Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

研究了1，2，4三酮3（TO）衍生物的合成，结果表明TO在多种硝化条件下均可制得3硝基1，2，4三酮5（NTO），同时还合成了TO的二取代硝基苯衍生物。