NK cell will trigger effector functions(cytolysis) by KAR,if target cell loses appropriate ligands recognized by KIR.

如果靶细胞失去KIR所识别配体，NK细胞即可通过KAR对靶细胞进攻击。

In addition, only certain murine mAb isotypes hae been shown to effectiely bind to and actiate elements of the human immune system, thereby triggering cytotoxic effector functions10.

另外，只有某些亚型鼠单抗可以有效结合并激活人免疫系统，以激发细胞毒作用[10]。