N-phosphoryl amino acids could be catalyzed by imidazole to result in solvolysis such as ester exchanges on phosphorus, esterification, formation of peptides and N→O migration of the phosphoryl group.
咪唑对磷化活化反应具有较强催化作用,磷化丝、苏在咪唑催化不仅能发生溶剂解反应,如磷上酯交换、羧活化成酯、成肽及磷N→O迁移等,而且还会发生分子内环化反应;