cyano 4’ methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%.
以溴化亚铜为催化剂,将邻苯甲腈与对溴甲苯偶联制备了合成沙坦类药物的
键中间体2氰基4′甲基联苯,收率50%。
cyano 4’ methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%.
以溴化亚铜为催化剂,将邻苯甲腈与对溴甲苯偶联制备了合成沙坦类药物的键中间体2氰基4′甲基联苯,收率50%。
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