喹诺酮

Quinolone is known as broad antibacterial spectrum,high potency,no crossing drugresistance with other antibacterial drugs,and easy and low cost to administer.

喹诺酮类药具有抗菌谱广、抗菌活性强、给药方便,与常用抗菌药无交叉耐药性、价格低等特点。

Finally, we gained four esterifiable quinolone analogues (compounds 22 to 25) by modifying the structures of compound 3, 14 and 16 on 3 position.

用所成的3，14，16为模板，对它们的3位羧基进行了酯反应成了4个喹诺酮酯类：22—25。