喹诺酮

Quinolone is known as broad antibacterial spectrum,high potency,no crossing drugresistance with other antibacterial drugs,and easy and low cost to administer.

喹诺酮类药物具有抗菌谱广、抗菌活性强、给药方便,与常用抗菌药物无交叉耐药性、等特点。

Finally, we gained four esterifiable quinolone analogues (compounds 22 to 25) by modifying the structures of compound 3, 14 and 16 on 3 position.

同时利用所成的化物3，14，16为模板，的3位羧基进行了酯化反应成了4个喹诺酮酯类化物：化物22—25。