Difloxacin is the fluorinated quinolone approved for use in veterinary only. compared to ciprofloxacin,it provided with better pharmacokinetical and pharmacodynamical feature.

二氟沙星属于兽医专用药，有优于环丙沙星药动学特征，有良好应用前景。

Finally, we gained four esterifiable quinolone analogues (compounds 22 to 25) by modifying the structures of compound 3, 14 and 16 on 3 position.

同时利用所化3，14，16为模板，对它们3位羧基进行了酯化反应了4个喹诺酮酯类化：化22—25。